Inherited Breast Cancer and Genetics

People who have inherited an altered gene will be at a high risk of developing breast cancer and possibly other cancers. Around 5% of women with breast cancer have inherited an altered gene. Most inherited cases of breast cancer are associated with two abnormal genes: BRCA1 (Breast Cancer gene one) and BRCA2 (Breast Cancer gene two). Breast cancer is the most common cancer in women in the western world. In breast cancer development, genetic and environmental factors play a role in family history being the most important factor in determining breast cancer risk. Cancers occur when a buildup of mutations in critical genes those that control cell growth and division or repair damaged DNA allow cells to grow and divide uncontrollably to form a tumor. In most cases of breast cancer, these genetic changes are acquired during a person's lifetime and are present only in certain cells in the breast. These genes are described as "high penetrance" because they are associated with a high risk of developing breast 

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  • Breast Cancer Immunotherapy
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