Gwennaëlle C.Monnot and her team have discussed on Breast Cancer Immunotherapy in the article entitled “Rationale for immunological approaches to breast cancer therapy”. This article was published in Journal “Breast Cancer” under the section “Breast Cancer Immunotherapy” published on 17 June 2017.
Immunotherapies are novel treatment modalities which aim to use immune mediators to attack cancerous cells. Recent clinical results show that these may not only mediate tumour regressions but also cures in some cases. In this review, we discuss the relevance of the immune system in the development of new carcinomas, as well as its importance in mediating cancer regression. We also dissect the known different approaches to harness the immune system to attack breast tumours. Namely, therapies using the passive transfer of either tumour-specific antibodies or cytotoxic cells have been researched and in some cases are already standard of care. Additionally, therapeutic vaccines and immune checkpoint blockade have recently demonstrated great therapeutic efficacy and have generated great excitement for the development of new treatments.
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